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Preclinical Metabolic Models: Cell and animal research has investigated NNMT inhibition in relation to adipocyte biology, cellular energy expenditure and metabolic signaling

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Notably, several immune signaling pathways, including Chemokine signaling pathway, Rheumatoid arthritis, Toll-like receptor signaling pathway, IL-17 signaling pathway and Complement and coagulation cascades, were also enriched in high-fat diet