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ArsR Members of the arsenic repressor (ArsR) superfamily sense a wide range of stimuli (Figure 10A) and feature a compact homodimeric winged helical DNA binding fold, characterized by a core 1-2-3-4-1-2-5 secondary structure, where the dimer is formed by the quartet of 2 and 5 helices from each subunit (Figure 10B)

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Progressive weakness, worsening balance problems, or new neurological symptoms require prompt assessment, as these may indicate inadequate treatment or concurrent conditions

D., Grespi, E., Cassinerio, E., Bignamini, D

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Accordingly, agents targeting the molecular participants in the Th2-high subtype (e.g., anti-IL-4, anti-IL-5, anti-IL-13, IgE blockers, and inhibitors of prostaglandin D2 (CRTH2) receptor) have recently been presented as potential drugs to treat asthma