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In preclinical models, both thymosin beta-4 and TB-500 have been observed to stimulate glial proliferation, enhance angiogenesis, and support neuronal survival following induced injury

MS is the most frequently observed demyelinating disease, with variable incidence (Korn 2008)

However, increasing the amount of GSH available to the system was able to moderate this response, reducing the severity of E hc disruption to notionally acceptable levels

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This stimulatory effect occurs through multiple mechanisms, including increased COL1A1 and COL1A2 gene transcription, enhanced procollagen mRNA stability, and improved post-translational processing of procollagen molecules

While we found a few of the complexes in the OM from cells depleted for GspD, we observed large numbers of such structures in the OM fragments from cells grown in the presence of copper (Fig