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4f, statistics were derived from Results were considered statistically significant at the following thresholds: * p 0.05, ** p 0.01, *** p 0.001 or **** p 0.0001

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TAM binds to the estrogen receptor to form a nuclear complex that blocks the estrogen receptor transcriptional activity, thereby reducing DNA synthesis and inhibiting the effect of estrogen (Karn et al., 2010)

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However, factors like aging, stress, UV exposure, lack of sleep, and alcohol consumption can significantly reduce glutathione levels in the body