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Comparative Antioxidant Profiles Property Glutathione (GSH) Ergothioneine (EGT) Redox activity Very high, dynamic Moderate, stable Chemical stability Low (constantly recycled) Very high Specific transporter No Yes (OCTN1/SLC22A4) Tissue accumulation Limited High (brain, liver, eyes) Mitochondrial protection Indirect (via GPx) Direct DNA protection Mitochondrial (primary) Nuclear and mitochondrial Intestinal degradation Partial Very low Human synthesis Yes (liver) No (dietary only) Mushrooms as the Only Known Source of Both Molecules While glutathione is also found in other foods asparagus, avocado, red meat ergothioneine is found almost exclusively in mushrooms

Areas where 3/7 or more participants showed an improvement of 2 points included the GI system, urinary system, sex and other functions, while 3/7 or more participants experienced a worsening of 2 points in sleep/fatigue

I.CrosnoeL

Indeed, in perisynaptic Schwann cells at the neuromuscular junction as well as in Schwann cells along the axons of the regenerating sciatic nerve, MT1 has become upregulated, thus leading to an elevated phosphorylation of ERK (Stazi et al., 2021)

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Glutathione can give you visibly healthier skin when used with compatible ingredients