Homologous recombination events were confirmed by Southern blot analysis, and positive clones were injected into blastocysts derived from C57Bl/6 mice
Thermo Fisher Scientific, Inc
The twice-daily approach maintains consistent peptide levels and enhanced fat oxidation throughout the day
The study addressed two questions: whether the fragment retained activity when delivered enterally rather than parenterally, and whether the effects observed in rodent models translated to human adipose tissue at the cellular level
1 Remove AOD-9604 vial from refrigeration and allow to reach room temperature (1520 minutes) 2 Clean vial top with alcohol swab and allow to air dry completely 3 Using a sterile syringe, draw the calculated volume of bacteriostatic water (BAC water) 4 Inject BAC water slowly down the side of the vial do not aim directly at the powder 5 Gently swirl in circular motions DO NOT shake vigorously as this degrades the peptide 6 Allow 23 minutes for full dissolution solution should be clear and colorless 7 Draw calculated dose into an insulin syringe for subcutaneous injection 8 Inject into abdomen, thigh, or upper arm
[63] Bettuzzi S, Brausi M, Rizzi F, et al
