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It possesses strong oxidative properties and can react with reductive substances or biomolecules within the cell, thereby regulating redox reactions and influencing the expression of intracellular signaling molecules [45]

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C677T Mutation: This mutation involves a change at position 677 in the MTHFR gene, where cytosine (C) is replaced by thymine (T)

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4-HNE is classified as an , -unsaturated aldehyde and possesses three functional groups: carbon-carbon double bonds, carbonyl groups and hydroxyl groups

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105 Another placebo-controlled trial in 60 PCOS-affected subjects found 250 mg magnesium oxide per day for eight weeks increased LH levels and reduced BMI but did not affect markers of glucose or lipid metabolism, or multiple indices of hormonal status

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