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The RAAS is considered to be a major activator of NADPH oxidase and ROS production in hypertension

Serum levels of lycopene, beta-carotene, and retinol and their correlation with sperm DNA damage in normospermic and infertile men

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For instance, we have shown that elderly patients with treated hypertension exhibit increased CuZn-SOD activity and elevated GSH levels (28), which may suggest that lowering blood pressure during antihypertensive treatment is at least in part due to a CuZn-SOD-GSH-dependent mechanism

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