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Twenty microliters of supernatant was transferred into a 96-well plate, and 200 l of 37 C o-dianisidine hydrochloride solution was added immediately before the optical density was read at 450 nm and again 30 s later, as previously described 26

Moreover, a novel mouse model engineered to have enhanced cholesterol synthesis by SREBP-2 overexpression superimposed to APP/PS1 mutations triggered A accumulation and tau pathology ( in vivo replenishment of mGSH with cell- permeable GSH monoethyl ester (GSHEE) attenuated neuropathological features of AD in SREBP-2/APP/PS1 mice

doi: 10.1371/journal.pone.0191159

doi: 10.1002/jsfa.4364 120