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The docking analyses revealed that the positioning of the GSH-thiolate in relation to C-2 and O-3 of the docked substrates could enable an acidbase mechanism of dehydration or tautomerization, in which the GSH cofactor acts as a proton-relay system (Fig

Xiao-Yan W, Xiao-Xia Y, Peng-Fei S, Zong-Xue Z, Xiu-Li G

How can side effects be minimized or managed during treatment

5-Lipoxygenase inhibition reduces inflammation and neuronal apoptosis via AKT signaling after subarachnoid hemorrhage in rats

racemization during synthesis or storage reduces potency substantially and is not detectable by standard reverse-phase HPLC (requires chiral HPLC)

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