BPC-157 significantly accelerates reticulin and collagen formation, as well as angiogenesis, along with macrophage stimulation and fibroblast infiltration, which is a potential therapeutic tool in the treatment of wound healing
As glutathione decreases, the lining of the blood vessels becomes less pliable and more resistant to widening when necessary for increasing oxygen transfer to tissues
Blind cage coding and automated video analysis (EthoVision, TopScan) are recommended Too low n : prior power analysis, n 8 minimum for rodent behavioural tests No positive control : without memantine, donepezil or scopolamine depending on the paradigm, impossible to judge if the model is functional No dose-response : a single tested dose is insufficient to conclude
Low-dose anti-thymocyte globulin (ATG) preserves beta-cell function and improves HbA1c in new-onset type 1 diabetes
the potential off-target effects of therapies targeting these pathways (e.g., disrupting normal lipid homeostasis in healthy tissues) have not been adequately addressed, and biomarkers to predict ferroptosis susceptibility via lipid/antioxidant signatures are still lacking
Both the megadose amount and the long term maintenance dose (up to 20g/day) seems unnecessarily high to me
