At baseline and at weeks 8 and 12, a clinician should assess fasting insulin and HOMA-IR (the homeostasis model assessment of insulin resistance, a calculated index derived from fasting glucose and insulin), HbA1c, high-sensitivity C-reactive protein as an inflammatory marker, and body composition by DEXA scan or bioelectrical impedance
Loss of appetite and weight loss: A reduced appetite can be a telltale sign, potentially leading to weight loss
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In practical terms, it accelerates healing in gut lining, tendons, ligaments, muscle, and joint tissue by restarting a repair process that has stalled or by supporting tissue that is under chronic inflammatory stress
But for most people, the effect is more of a gradual return to your normal baseline, not a sudden, dramatic spike in energy