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Nguyen D, Alavi MV, Kim KY, Kang T, Scott RT, Noh YH, et al

doi: 10.3390/ph18121822

Hypertrophy + hyperplasia Animal-model research shows IGF-1 LR3 drives both fibre growth (hypertrophy) and new fibre formation (hyperplasia) - distinct from most anabolic agents

Bypasses first-pass metabolism entirely, achieving 100% bioavailability at peak plasma concentrations within minutes

Mutated NPM1 in patients with acute myeloid leukemia in remission and relapse

Fixing testosterone-cortisol balance by means of a novel dual-hormone clamp mitigates the induction of insulin resistance by sleep restriction and provided the first proof-of-concept that the metabolic harm from sleep loss can be ameliorated by approaches that do not require sleeping more