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Metabolites (2020)

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Levels of plasminogen activator inhibitor-1 (PAI-1) and tPA antigens were determined by ELISAs (Hyphen BioMed, Neuville-Sur-Oise, France), while PAI-1 activity was evaluated using a chromogenic assay (Chromolize PAI-1, Trinity Biotech, County Wicklow, Ireland)