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Another aim was to combine several plants or their purified ingredients into new multitarget hybrid combinations with more effective pharmacological activity
Promote renal calcium reabsorption Renal tubular calcium transport: upregulate the expression of renal tubular calcium channel (TRPV5), reduce urinary calcium excretion by 30% -40%, increase blood calcium concentration, and increase bone calcium deposition Evidence from preclinical studies on AOD 9604 bone protection (animal experiments) Postmenopausal osteoporosis (OVX rat model) Experimental Design: Animal: 6-month-old female SD rats underwent bilateral ovariectomy (OVX) to establish a postmenopausal osteoporosis model
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In addition to drinking alcoholic beverages and merely getting older, these are common household chemicals that can reduce the bodys glutathione levels (7, 8, 9, 10): Both chronically low and high levels of glutathione in the body are indicative of potentially debilitating health problems
