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Sci Total Environ 573:727739

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These results indicated significant and distinct alterations in iSPN + mut neurons at the pre-symptomatic stage

Another emerging approach involves the use of personalized peptide-based vaccines based on neoantigens to enhance antitumor response

The signal transducer and activator of transcription 3 (STAT3) protein is a transcription factor known to stimulate immunosuppressive cells, e.g., myeloid-derived suppressor cells (MDSC) and regulatory T cells (Treg), activated in chronic inflammatory conditions [8, 9]

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