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However, A plaques in these spaces can lead to reduced expression of AQP4 at the astrocytic end-feet, adversely affecting A efflux with the ISF and exacerbating intraparenchymal A deposition [58, 173, 174]

Infection stage annotation was based on marker genes from Gene Expression Omnibus (GEO) dataset GSE150484

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doi: 10.1016/s0969-2126(98)00022-7

Br J Dermatol 187(6):866877

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