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Yang et al., 2014), and suppress cytokine signaling protein SOCS3 (Li et al., 2018), matrix metalloproteinase MMP9 and angiogenesis factor VEGF (Li et al., 2010

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It hurts in my shoulders.[181] Musculoskeletal Disorders Engaging in repetitive motions and carrying heavy loads can lead to musculoskeletal disorders, defined by the United States Centers for Disease Control and Prevention as, injuries or disorders of the muscles, nerves, tendons, joints, cartilage, an disorders of the nerves, tendons, muscles and supporting structures of the upper and lower limbs, neck, and lower back that are caused, precipitated or exacerbated by sudden exertion or prolonged exposure to physical factors such as repetition, force, vibration, or awkward posture.[182] The ILO considers musculoskeletal disorders arising from repetitive work, working in unsuitable positions, carrying heavy loads among the major occupational and work-related diseases affecting agricultural workers worldwide.[183] A 2010 review of musculoskeletal disorders in agricultural work cites three main risk factors for such injuries: lifting and carrying heavy loads, sustained or repeated full body bending, and very highly repetitive hand work.[184] Children may be especially vulnerable to musculoskeletal disorders because their bodies are still developing.[185] The impacts of repetitive strain injuries may be long-lasting and result in long-term health consequences including chronic pain and arthritis.[186] IV

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