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The ex vivo synthesized sequences of FAPCAR were cloned into IVT template plasmid as the ORF region which also carried T7 promoter, modified 5 UTR, kozak sequence, 3 UTR, and a 110 nt-long poly (A) tail 59,60,61
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What to Expect in Month 1 Appetite changes: Noticeable suppression begins week 3-4 for most Mild nausea: 40% experience some nausea, usually mild Injection site reactions: Redness, itching, or mild pain at injection site (14% of patients) Fatigue: Some patients report low energy as body adjusts Bowel changes: Either constipation or looser stools as medication affects gut motility 4 Essential Strategies for Month 1 1
