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Harrisons principles of internal medicine
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The gut microbiome as a target in cancer immunotherapy: opportunities and challenges for drug development
At the start of the study, the people involved in the study weighed an average of about 240 pounds
Short-chain fatty acids (SFCAs) like acetate, butyrate and propionate, derived from host microbial fermentation of non-digestible carbohydrates, transduce signals through GPCR to promote anti-inflammatory cytokines (IL-10, IL-18) and Treg responses [198, 199] These SCFAs also suppress pro-inflammatory histone deacetylase (HDAC), NF-B and nitric oxide production, thus diminishing oxidative stress-induced epithelial cell apoptosis, and exerting a protective effect on colonic and cardiac health [199]
Building and maintaining muscle mass can therefore elevate your basal metabolic rate, making it easier to manage weight in the long term
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