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The goal is to support metabolism, increase energy, and maintain healthy levels of essential vitamins, since B12 deficiency is a possible side effect of some weight loss medications

Unlike earlier broad-spectrum senolytics that can harm healthy tissue, FOXO4-DRI targets a molecular interaction unique to senescent cells

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However, in the 1980s this hypothesis was changed by the identification of IGF-I production in numerous tissues (Figure 6)