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Telomerase activation pathway Epitalon's primary mechanism involves activating telomerase through upregulation of the hTERT gene, which codes for the catalytic subunit of telomerase

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25 subjects treated for 10 weeks showed a mean Y-BOCS improvement of 20%

27 These observations suggested that erastin-induced ferroptosis is clearly distinct from autophagy, apoptosis, and known forms of necrosis

Eur J Hum Genet 2017;25:886-8

Use of the arginine-depleting agent pegylated arginine deiminase ADI-PEG20 in GBM can increase nitric oxide (NO) synthesis and produce cytotoxic pernitrite, increasing the sensitivity of tumor cells to ionizing radiation and significantly enhancing the effect of radiotherapy on GBM