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In one study, Dzitoyeva and colleagues observed that 5-hydroxymethylcytosine levels in mtDNA decreased with aging and a higher expression of genes encoded by mtDNA were seen in the frontal cortex of 4- and 24-month-old mice [122]

Particulate matter with a diameter of 2.5 m (PM 2.5 ) can reach the alveoli and has been associated with heart disease and lung cancer 263,266,267,269

In another human study, Epitalon was applied to PHA-stimulated lymphocytes from adult donors aged 25 to 88 years

2013Nov;48:12051212

Chung MK, Chung RP and Gordon D: Interstitial cystitis and endometriosis in patients with chronic pelvic pain: The "evil twins" syndrome

The paper synthesises existing research and adds gene expression analysis but does not generate new patient data