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Patients with pernicious anaemia or complete malabsorption typically require lifelong treatment at standard intervals, while those with partial malabsorption may have variable needs

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Patients taking nitroglycerin for angina should be particularly cautious, as sublingual medications can potentially alter the absorption of nitroglycerin, which could affect its therapeutic efficacy

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Researchers measure outcomes such as cell proliferation rate, migration assay results, collagen secretion (via ELISA or hydroxyproline assay), and gene expression changes via quantitative PCR or transcriptomics