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the S in SPRINT stands for Systolic, so they did not address the diastolic component) Their conclusion was that aggressive antihypertensive drug therapy in this study population was safe and effective

Kurth T, Kase CS, Berger K, Gaziano JM, Cook NR, Buring JE

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Whether the significant, but rather subtle reduction in the acyl chain length observed in the skin of smokers in this study could affect the overall barrier function remains unclear

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