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CVD risks were elevated at almost all levels of current smoking intensity examined and increased with smoking intensity, with HRs for total CVD mortality in current versus never smokers of 1.92 (1.113.32) and 4.90 (3.796.34) for 46 and 25 cigarettes/day, respectively

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In fact, it had been suggested as a possible protective factor against the disease, associated with the effect of nicotine

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