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The novelty of this review lies in its integrative approach, moving beyond a mere description of disparate pathways to synthesize a coherent framework that connects key metabolic nodessuch as the mammalian target of rapamycin (mTOR)-hypoxia-inducible factor 1-alpha (HIF-1)-glycolysis axis, AMP-activated protein kinase (AMPK)-FAO signalinginto a dynamic immunometabolic network ( Figure 1 )

The gpoA mutant exhibited diminished survival across multiple organs relative to the wild-type strain, suggesting that GpoA contributes to pneumococcal pathogenesis

Non-laser light sources such as conventional lamps can be coupled to optical fibers to set the light wavelength

Instead of overwhelming the body with external hormones, it restores natural production patterns

We continue to the town of Tinqui (3,900 m.a.s.l.), where we spend the night camping