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This often happens if you skip meals, eat irregularly, or have certain medical conditions like diabetes

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Bioprocess Biosyst Eng 33:675682 Liao X, Deng T, Zhu Y, Du G, Chen J (2007) Enhancement of glutathione production by altering adenosine metabolism of Escherichia coli in a coupled ATP regeneration system with Saccharomyces cerevisiae

[18] Additionally, very high doses of folic acid could potentially mask a B deficiency, so its important your doctor knows about any folate supplements you take