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Freezethaw cycles may: Affect molecular stability Increase aggregation risk in some formulations Reduce overall consistency of the solution Storage at 28C is typically preferred unless otherwise validated
Safety and Preliminary Efficacy of Intranasal Insulin for Cognitive Impairment in Parkinson Disease and Multiple System Atrophy: A Double-Blinded Placebo-Controlled Pilot Study
Y. Fan, Y. Gong, P. K. Ghosh, L. M. Graham, and P. L. Fox, Spatial Coordination of Actin Polymerization and ILKAkt2 Activity during Endothelial Cell Migration, Elsevier BV, May 2009. doi: 10.1016/j.devcel.2009.03.009
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[PubMed] [Google Scholar] 147.Timimi K.S., Bedwani J.R., Stanton T.W
[11] This indicates that animal reproduction studies have shown an adverse effect on the fetus, and there are no adequate, well-controlled studies in pregnant women
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