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Furthermore GSTO-1 modulates rynodyne receptors thereby protecting cells against Ca 2+ induced apoptosis and inhibition of the posttranslational processing of pro-inflammatory cytokine interleukin-1 [20, 21]

Bi-allelic variants in COL3A1 encoding the ligand to GPR56 are associated with cobblestone-like cortical malformation, white matter changes and cerebellar cysts

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, the production of both superoxide and NO is increased 1,000-fold, which will increase the formation of peroxynitrite by 1,000,000-fold [74]