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M., Fanning, M

SLC7A11 and SLC3A2 mediate ER inhibition of ferroptosis in ER+ breast cancer cells To investigate whether SLC7A11 and SLC3A2 are involved in ER-regulated ferroptosis, we examine the effects of knocking down SLC7A11 and SLC3A2 using two different shRNAs in ER+ breast cancer cells (Fig

GLYCOLYTIC INTERMEDIATES GENERATE CYTOSOLIC NADPH THROUGH THE PENTOSE PHOSPHATE PATHWAY (PPP) The oxidative phase of the pentose phosphate pathway (PPP), also called the phosphogluconate pathway and hexose monophosphate shunt, is one of the primary sources of cytosolic NADPH (Fig

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