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Hardie LJ, Briggs JA, Davidson LA, Allan JM, King RF, Williams GI, Wild CP

2016;19(9) Patil SP, Jain PD, Ghumatkar PJ, et al

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The researchers utilized advanced mass spectrometry and RNA-sequencing to map the exact metabolic dysfunctions driving these conditions, uncovering striking evidence of severe oxidative stress and mitochondrial lipid oxidative damage mediated by glutathione peroxidase 4, as documented in the PNAS metabolic study

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