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Many people are surprised to learn that vitamin B12 deficiency is a recognised contributor to nerve damage

In StatPearls

Disulfide Bond Integrity Verification (Cys7-Cys14) Because the Cys7-Cys14 intramolecular disulfide bond is required for the lipolytic conformation, every lot is checked for disulfide bond integrity using non-reducing LC-MS or Ellman's reagent analysis

Deficiency has been recognized in infants of vegetarian mothers who were breast fed, even though the mothers had no symptoms of deficiency at the time