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Most, if not all, e-cigarette companies promote the same list of 4 base e-liquid ingredients in their products: propylene glycol, vegetable glycerin, flavoring (both natural and artificial) and nicotine

Former FDA Commissioner Scott Gottlieb and other public health officials have termed such use an "epidemic", and Commissioner Gottlieb considered this issue a priority during his tenure

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This data indicates a slightly higher tendency for rural smokers to receive professional advice and assistance, with urban smokers showing a greater reliance on counseling

The agency has in particular taken heat over its part in approving the drugs at the center of the national opioid epidemic