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Indeed, conceptually, it would be critical to monitor the progressive pathological changes of these markers throughout adulthood, so to identify subjects possibly at risk of developing a neurodegenerative process favoured by the presence of OS induced, at least in part, by an imbalance of the KEAP1-NRF2 system
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The pathogenesis of IBD is not fully understood but involves complex interactions among genetic predisposition, immune dysregulation, environmental factors, and intestinal microbiota changes
doi: 10.1016/j.ecl.2012.04.017 99 HottaMShibasakiTMasudaAImakiTSuginoNDemuraHet al
10.1002/mc.20553 [DOI] [PMC free article] [PubMed] [Google Scholar] Yang, J
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