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GSEA was performed using the clusterProfiler and msigdbr R packages ( Heatmaps were generated using Morpheus (Broad Institute)

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109 The Nrf2 coordinates the basal and stress-inducible activation of the glutamate-cysteine ligase complex 110 and regulates the transcription of glutathione peroxidase 2 and glutathione S-transferases

Altered dopamine and opioid receptor signaling, which are like those seen in substance use and addictive disorders, have been observed in high-fat diet animal studies (132)

Traditional methods are about managing, removing, or attempting a repair in a low-success environment