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In several species, including humans, this damage has recently been linked to degenerative diseases such as rheumatoid arthritis, cancer, cardiovascular disease, inflammatory bowel disease, renal disease, Parkinsons disease, and cataracts

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Infertility can be caused by various mechanisms, including steroidogenic pathway defects, pro and antioxidant activity imbalances, apoptotic pathway irregularities, pro and anti-inflammatory markers, and reactive oxygen species production (El-Hanoun et al., 2020)

(2016) 5:e002767

10.1016/j.arr.2021.101395 58 CollaboratorsG.NicholsE.AbdAllahF.AbdoliA.AbosetugnA