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Pushing a single peptide to its ceiling is where the harshest side effects tend to live, because you are forcing one receptor system to do everything

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I recommend avoiding them: Escharotic treatments, which can do serious damage to the cervix, even when used under the care of an experienced naturopath or MD Thuja, which can be toxic if systemically absorbed at a high enough dose

Ultrastructure of the resting ovarian follicle pool in healthy young women

Kruse T, Hansen JL, Dahl K, Schffer L, Sensfuss U, Poulsen C, Schlein M, Hansen AMK, Jeppesen CB, Dornonville de la Cour C, Clausen TR, Johansson E, Fulle S, Skyggebjerg RB, Raun K

The best way to treat melasma depends upon the individual, but all treatment needs to include both active treatments to remove the pigment in the skin AND a proactive skincare and medication routine to prevent new pigment from developing