In both NAFLD mouse models and FFA-induced hepatocyte models, BMP4 upregulation enhances GPX4 expression at both the gene and protein levels, suggesting a protective role against ferroptosis
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Neuschwander-Tetri BA, Loomba R, Sanyal AJ, Lavine JE, Van Natta ML, Abdelmalek MF, Chalasani N, Dasarathy S, Diehl AM, Hameed B, Kowdley KV, McCullough A, Terrault N, Clark JM, Tonascia J, Brunt EM, Kleiner DE, Doo E (2015) Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial
The cytotoxic role of RREB1, ZIP3 zinc transporter, and zinc in human pancreatic adenocarcinoma
As an antidote to acetaminophen poisoning, NAC restores the hepatic GSH pool depleted in the drug detoxification process
In doing that, Ive had the opportunity to interact with many people in the glaucoma field, so to speak