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In addition to sleep function, the peptide has been documented to affect neurotransmitter levels in the brain, hormonal levels, psychological performance, and the activity of pharmacological drugs [4, 6, 7, 9]

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By disrupting the FOXO4-p53 interaction, FOXO4-DRI, a specific FOXO4 blocker, selectively induced p53 nuclear exclusion and apoptosis in senescent Leydig cells

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