Histone methylation and the DNA damage response
[DOI] [PMC free article] [PubMed] [Google Scholar] [57].Skaggs BJ, Singh RP, Hahn BH
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Indian Journal of Clinical Anaesthesia
The lack of immunogenicity has practical implications: the peptide can be used for extended periods without loss of efficacy due to antibody neutralization, there is minimal risk of allergic or hypersensitivity reactions, and repeated treatment cycles are supported as prior exposure does not sensitize the immune system
In vivo , in an AIA rat model, the circulation half-life of HA@M@PB@SINNPs at the site of arthritis reached 6.51 h, which is eight times that of free sinomenine hydrochloride (SH), significantly enhancing drug accumulation