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Therefore, GLT2iinduced ketosis might represent one of the beneficial effects of these drugs, together with reduced plasma volume due to osmotic diuresis, decreased body weight, reduced arterial blood pressure levels, and improvement in sympathetic nervous system activity, glycemia, and hyperuricemia (109111)

Cell pellets were re-suspended in 100 L PBS

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As a serine protease, hepsin presents challenges for administration as an intact or activated protein due to its tendency to auto-activate, degrade, and its overall instability (Li et al

The critical variable is cumulative thermal exposure