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Most animals have a circadian rhythm and their bodies release the sleep hormone, melatonin, in the night

P.CourcolR.VincentP.JonckheereN.et al (2014)

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In this article, we will explore some of the various theories that are currently in circulation, which outline the cause as: Excessive production of porphyrin by skin bacteria stimulated by B12 A cobalt allergy Relative deficiency of vitamin B12 cofactors A detoxification reaction Vitamin B12 Acne The Work of Skin Bacteria

doi: 10.3390/biology11020159 21 Beltrn-GarcaJ.Osca-VerdegalR.PallardF