Manoguerra AS, Erdman AR, Booze LL, et al
Mechanisms differ, and they can be synergistic
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[211] Healthcare providers typically recommend taking melatonin 1 to 3 hours before desired bedtime to allow adequate time for absorption and onset of effects
Medications like methylphenidate, which primarily target dopamine and norepinephrine, are effective in improving symptoms in around 60-70% of patients
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