Currently, only two germ line missense mutations of c-MET have been found within B cell lymphoma, especially DLBCL (R1166Q in the tyrosine kinase domain in one patient and R988C in the juxtamembrane domain in four patients) [28]
Levy et al, 2018
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The activity of NMNAT1 is essential for axon survival because activity reduced mutants have no axon protection effect
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Western blot analysis further confirmed that H2O2 treatment led to increased levels of senescence-associated proteins p53, Ser15-phospho-p53, and p21
