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For most healthy adults, daily supplementation with glutathione is considered safe and is often necessary to maintain consistent levels in the body

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As indicated in Figure 2, oxidized GSH is recycled back to GSH by glutathione reductase (GR) with the consumption of nicotinamide adenine dinucleotide phosphate (NADPH)

Aditi Stanton, MD, a gastroenterologist at Gastro Health in Cincinnati, Ohio