Studies in Europe and North America suggest that e-cigarette use in adolescent non-smokers may be a gateway drug associated with future uptake of tobacco cigarette smoking, marijuana use, and the use of other tobacco products like hookahs, cigars, and pipes
Since 2013, he has been working with LabX Media Group developing content solutions that engage and inform scientists and laboratorians
Furthermore, e-cigarettes are thought to increase dual smoking and downstream substance use through the gateway hypothesis, whereby exposure to nicotine products further puts individuals at risk of initiating other substances by stimulating neurotransmitters associated with the reward system 4,55,71,72,73
When inhaled rapidly in cigarette form, these nuances are lost and the harshness increases
"Comprehensive smoke-free legislation in England: how advocacy won the day." Tobacco Control 16.6 (2007): 423-428.online Shahab, Lion, and Robert West
However, thats just my personal experience, and truth be told, I havent tried a ton of different juices