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It is a membrane stabilizer and counteracts gut-leaky syndromehas profound cytoprotective activityand specifically [controls] the VEGF [vascular endothelial growth factor] and NO [nitric oxide] pathways, in particular the prostaglandin pathway (Sikiric et al, 2022)

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Certain B vitamins, particularly vitamin B6 and B12, are excreted through the kidneys, and accumulation may occur in severe renal dysfunction

Because BPC-157 is derived from a compound found in gastric juice, much of the early research examined its protective effect on the stomach and intestinal lining in animal models