Also known as cobalamin, it is a water-soluble vitamin essential for neurological function and DNA synthesis
NNMT activity returns to baseline within 4872 hours, and mitochondrial NAD+ levels normalize accordingly
High B12 blood levels should always be examined further, in order to rule out any serious diseases
It is important to use them carefully and with guidance from healthcare professionals to ensure they are safe and effective
Foundational NNMT Discoveries The foundational research establishing NNMT as a metabolic regulator and potential therapeutic target came from studies by Daniel Kraus and colleagues published in Nature in 2014, which demonstrated that NNMT expression is dramatically upregulated in adipose tissue of obese humans and diet-induced obese mice, and that genetic knockdown of NNMT in mice protected against diet-induced obesity and improved metabolic parameters
For those managing diabetes with injectable medications, understanding storage is familiar territory
