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This profound demographic shift marks the advent of a new era characterized by population aging [3,4,5].Meanwhile, global average life expectancy has risen from 46.5 years in 1950 to 71.7 years in 2022, and is projected to reach 77.3 years by 2050 [2]

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Subcutaneous tumours grown in athymic nude mice were randomized when the average tumour volume reached 100 mm 3 and were allocated to one of four treatment groups: saline control

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Kenyon, C., Chang, J., Gensch, E., Rudner, A